News and Events / Media

From the CEO's Desk

Swaroop Vakkalanka, PhD

Founder & CEO

My tryst with biotech R&D has been exciting and mutually rewarding in the last 25 years. There is a constant need for innovative therapies that could influence human lives positively.

Rhizen Pharma was founded with a vision to discover and develop novel onco-therapeutics designed to improve the quality of life of patients and drive transformative outcomes.

Rhizen is deeply committed to fulfilling this vision to address the immense unmet need that exists for patients living with cancer.

At Rhizen we practice

Fostering a culture of cutting-edge innovation as has been evidenced by our pivotal leadership in the “Targeted Drugs for Oncology & Inflammation” space through our focus on platforms that are fortified with foundational and expansive assets

Staying focused on the patient care with a relentless drive; tracking the evolution of relevant biology and explore remedies for challenges thrown

Creative collaboration and partnerships across global markets and research institutes

Purposeful communication to ensure the team’s focus on imaginative outcomes As we head into 2025 with aspirations to grow as full-fledged development company,

I firmly believe we are poised to make tangible difference to cancer care and to potentially bring to market innovative medicines. This is at the core of our philosophy and shapes the values at our company.

Latest News

Rhizen Pharmaceuticals Announces US FDA Acceptance of its IND Application for RP7214 in SARS-CoV-2 Infection; Phase 1 Clinical Trial of RP7214 Set to Begin Early December 2020

LA CHAUX DU FONDS, Switzerland--(BUSINESS WIRE)--Rhizen Pharmaceuticals, a clinical-stage oncology-focussed biopharmaceutical company, today announced the approval of its Investigational New Drug (IND) application by the U.S.

Rhizen Pharmaceuticals S.A. and Curon Biopharmaceutical Limited Announce an Exclusive Licensing Agreement to Develop and Commercialize Tenalisib, a Dual PI3K Delta and Gamma Inhibitor for Oncology in Greater China

Exclusive licensing agreement for the development and commercialization of Tenalisib, a dual PI3K delta & gamma inhibitor in the Greater China region.

Rhizen Pharmaceuticals AG Announces First Patient Dosed in a Phase 2 Study of RP7214 in Covid-19 Patients

First study of RP7214, a DHODH inhibitor, in Covid-19 patients with mild, symptomatic disease on the background of promising preclinical efficacy & Phase 1 healthy volunteer safety

Rhizen Pharmaceuticals AG Announces First Patient Dosing in a Phase II Study of Tenalisib (RP6530) in Locally Advanced or Metastatic Breast Cancer Patients

Rhizen Pharma commences dosing in a phase II trial to evaluate Tenalisib (RP6530; isoform selective dual PI3K δ/γ inhibitor with additional SIK3 activity) in patients with locally advanced or metastatic breast cancer.

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Recent Publications

RP6557, a novel, and selective PI3K δ/γ inhibitor, demonstrates efficacy in preclinical models of pulmonary fibrosis (Discovery on Target 2021)

Dual inhibition of the delta and gamma isoforms of PI3K by RP6557 attenuated PDGF induced lung fibroblast proliferation and TGFβ-mediated IL-6 release. Effective translation of activity in an animal model of pulmonary fibrosis with potent antiinflammatory and anti-fibrotic activity especially in combination with pirfenidone

1365: Safety and Efficacy of Tenalisib Given in Combination with Romidepsin in Patients with Relapsed/ Refractory T-Cell Lymphoma: Final Results from a Phase I/II Open-Label Multi-Center Study (ASH 2021)

The combination of tenalisib and romidepsin demonstrated a favorable safety profile and promising anti-tumor activity in patients with R/R TCL

1233: Preclinical profile of RP12146, a novel, selective, and potent small molecule inhibitor of PARP1/2. (AACR 2021)

RP 12146 demonstrated growth inhibitory activity in BRCA mutant and non-BRCA mutant cancer cell lines, and anti-tumor activities in both tumor size and tumor weight in OVCAR-3 xenograft model.

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